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. 2019 Oct 17;17:109. doi: 10.1186/s12951-019-0540-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Antitumor efficacy of HPPDC nanoparticles in MCF-7/ADR tumor-bearing mice. a Picture of the tumors removed from the mice with treatments of normal saline (the control), free CXB, free DOX, HPPD nanoparticles, DOX/CXB mixture, PPDC nanocores, and HPPDC nanoparticles. b Tumor growth curves of the mice with various treatments. c Body weight changes in the mice with various treatments. d H&E stained microscopical images of the major organs and tumors removed from the mice after various treatments. ** indicates P < 0.01 compared to the control; ^# indicates P < 0.05 for comparison between two treatment groups