Table 1.

Comparison of specifications for 3 optical endomicroscopy technologies

	eCLE	pCLE	VLE
Company	Pentax, Tokyo, Japan; and Optiscan, Victoria, Australia	Mauna Kea Technologies, Paris, France	NinePoint Medical, Cambridge, MA
Model	Pentax ISC 1000	Cellvizio 100 Series	Nvision VLE
Data Format	Surface images	Surface image video	Helical scan video
Axial Information	Multiple z-planes	Single z-plane	Multiple z-planes
Axial resolution, µm	7	NA	7
Lateral resolution, µm	0.7	3.5	NA
Z-depth, µm	0–250	60	0–3000
Frame size	$500\times 500$	600-µm diameter	6-cm scan acquisition length
Image size	$1024\times 1024$	$580\times 576$	NA
Speed	0.8-1.2 frames/s	12 frames/s	1200 slices/90 s
Intravenous fluorescein required?	Yes	Yes	No

eCLE: endoscope-based confocal laser endomicroscopy; NA: not applicable; pCLE: probe-based confocal laser endomicroscopy; VLE: volumetric laser endomicroscopy.