Table 3.
KEGG functional enrichment analysis of common targets (top 10).
| Term | Fold enrichment | Related targets | FDR |
|---|---|---|---|
| hsa05200: Pathways in cancer | 5.739 | PRKCA, AR, IL6, PTGS2, RXRA, RELA, PPARG, STAT1, MMP1, AKT1, CASP3, CASP9, JUN, BAX, BCL2, CASP8, MAPK8, NOS2, IKBKB, GSTP1 | 4.45E-07 |
| hsa04668: TNF signaling pathway | 12.647 | VCAM1, AKT1, ICAM1, CASP3, IL6, PTGS2, RELA, JUN, CASP8, MAPK8, IKBKB, SELE | 1.69E-06 |
| hsa05152: Tuberculosis | 8.9197 | AKT1, CASP3, IL6, CASP9, BCL2, RELA, BAX, CASP8, MAPK8, LBP, PPP3CA, NOS2, STAT1, CD14 | 3.06E-06 |
| hsa05161: Hepatitis B | 10.11 | PRKCA, IL6, RELA, STAT1, AKT1, CASP3, CASP9, BCL2, BAX, JUN, CASP8, MAPK8, IKBKB | 3.49E-06 |
| hsa05145: Toxoplasmosis | 11.277 | AKT1, CASP3, CASP9, RELA, BCL2, CASP8, MAPK8, ALOX5, NOS2, IKBKB, STAT1 | 3.40E-05 |
| hsa04620: Toll-like receptor signaling pathway | 10.639 | AKT1, IL6, RELA, JUN, CASP8, MAPK8, LBP, IKBKB, STAT1, CD14 | 3.26E-04 |
| hsa04932: Non-alcoholic fatty liver disease (NAFLD) | 8.2151 | AKT1, CASP3, IL6, RELA, JUN, RXRA, BAX, CASP8, MAPK8, IKBKB, INSR | 6.91E-04 |
| hsa04210: Apoptosis | 14.551 | AKT1, CASP3, CASP9, RELA, BAX, BCL2, CASP8, IKBKB | 0.001105 |
| hsa05164: Influenza A | 7.1292 | PRKCA, AKT1, ICAM1, IL6, CASP9, RELA, JUN, PRSS1, MAPK8, IKBKB, STAT1 | 0.002545 |
| hsa05204: Chemical carcinogenesis | 11.277 | GSTM1, CYP3A4, GSTM2, CYP1B1, CYP1A1, PTGS2, CYP1A2, GSTP1 | 0.006317 |