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. 2019 Oct 17;31(16):1235–1252. doi: 10.1089/ars.2019.7750

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© Verena Nadin Fritsch et al. 2019; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 3. — The mhqRED operon (SACOL2531-2529) is strongly upregulated in the RNA-seq transcriptome of S. aureus COL under MHQ stress and fully derepressed in the mhqR mutant. The mapped cDNA reads for the transcription profile of the mhqRED locus under control and MHQ stress are shown as displayed in Read Explorer (28). Transcription of the mhqRED operon is 35- to 67-fold induced under MHQ stress in S. aureus COL and most strongly derepressed in the mhqR mutant under control conditions (206- to 891-fold). Thus, mhqR encodes for a MarR-type transcriptional repressor of the mhqE and mhqD genes that encode for a dioxygenase and phospholipase/carboxylesterase, respectively.