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. 2019 Oct 16;8(11):585–605. doi: 10.1089/wound.2019.1046

Table 2.

Effect of nutrition factors on spinal cord injury therapy

Nutritional factor Effect Adjustment Source
NEG Promotes neuronal survival, growth, and axonal regeneration Widely expressed throughout the body, high expression of SCI First found in mouse sarcomas95,123
BDNF Axonal growth that promotes neuronal survival Wide expression throughout the body First discovered in the pig brain102
NT-3 Promotes the survival of sympathetic and sensory neurons Widely distributed in the body Cell gene regulation can be secreted123
CNTF Promotes neuronal survival, growing, and sprouting High expression of SCI First discovered in the ciliary ganglia of chicken embryonic eye tissue110,111
FGF Inducing angiogenesis at the injury site Wide expression throughout the body Secreted by the pituitary and hypothalamus115
GDNF Maintaining neuronal survival, reduces the production of glial scars Wide expression of the nervous system SC secretion117,124

CNTF, ciliary neurotrophic factor; FGF, fibroblast growth factor; GDNF, glial cell-derived neurotrophic factor.