Table 6.

Inflammatory Indices, Malondialdehyde And Total Antioxidant Capacity Measurement At Study Baseline And 12 Weeks After The Intervention In Subjects Who Received Either Saffron Or Placebo

Variables	Saffron Groupa		P-valueb	Placebo Groupc		P-valueb	P-valued
Baseline	After	Baseline	After
TNF-α (mg/dL)	19.1±8.1	18.3±7.8	0.147	18.3±7.9	17.3±6.5	0.076	0.796
hs-CRP (mg/dL)	2.7±1.1	2.5±1	0.016	2.5±0.9	2.4±0.8	0.557	0.124
MDA (μM/L)	17.8±0.17	16.7±3.5	<0.001	15.8±2.7	15.9±2.7	0.760	0.001
TAC (μM/L)	2.04±0.7	1.98±0.6	0.03	2.11±0.6	2.1±0.6	0.273	0.230

Notes: ^aReceived 100 mg saffron per day during the study. ^bObtained from paired-samples t-test. ^cReceived 100 mg placebo per day during the study. ^dObtained from independent-samples t-test.

Abbreviations: TNF-α, tumor necrosis factor-alpha; hs-CRP, high-sensitivity C-reactive protein; MDA, malondialdehyde; TAC, total antioxidant capacity.