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. 2019 Oct 11;9:1042. doi: 10.3389/fonc.2019.01042

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Copyright © 2019 Li, Eguchi, Aly, Chintala, Tan, Zauderer, Dembitzer, Beasley, Ghebrehiwet, Adusumilli and Peerschke.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan-Meier analysis of overall survival of patients with epithelioid MPM in the No-NAC cohort based on tumoral CD 4 lymphocyte infiltration and gC1qR expression. Tumoral infiltration by CD 4 lymphocytes is not associated with a statistically significant increase in OS (A), although a trend can be observed. Stratification of patients based on low (B) and high (C) gC1qR H scores, however, demonstrates a marked increase in overall survival in patients whose tumors demonstrate high gC1qR H scores and high CD4 lymphocyte infiltration.