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. 2019 Sep 13;4:32. doi: 10.1038/s41392-019-0060-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — E6 promotes cell proliferation through translational activation of the WNT/PCP/JNK pathway. a, b Growth curves of HeLa cells infected with lentivirus expressing the indicated shRNAs (indicated by ‘sh’) or genes (indicated by gene symbols). The data represent means ± SEM from at least three independent experiments (*p < 0.05, **p < 0.01, ***p < 0.001). c–f Actively proliferating HeLa cells infected with lentivirus expressing the indicated shRNAs or genes are shown by immunofluorescent staining for Ki-67. Representative images are shown in c and e, and the quantification of Ki-67 signals is plotted in d and f. ‘n.s.’ denotes ‘not significant’. The scale bars represent 25 μm. The data represent means ± SEM from at least three independent experiments (*p < 0.05, ***p < 0.001)