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. 2019 Sep 13;4:32. doi: 10.1038/s41392-019-0060-y

Fig. 5.

Fig. 5

E6 correlates with the WNT4/JIP2/JNK pathway in human cervical adenocarcinoma (CAC). a, b IHC staining of the indicated proteins in a human CAC tissue array containing 20 intact cancer tissues and 4 normal adjacent tissues (NATs) or normal cervical tissues. Representative images are shown in a, and the H-score-based quantification results are shown in b. **p < 0.01. c Staining scores from b were subjected to correlation analyses for E6 and WNT4, JIP1 or JIP2. d The mRNA expression levels of WNT4, JIP1, and JIP2 in the cancer cells of 52 CAC patients and 3 NAT/normal cervical tissues from TCGA are plotted as bar graphs. The data represent means ± SEM. ‘n.s.’ denotes ‘not significant’