Table 2.
Medical history and clinical findings in patients with PMR by agreement on diagnosis or fulfilment of classification criteria
| All | Supported a PMR | ACR/EULAR fulfilled | Bird fulfilled | Healey fulfilled | |
|---|---|---|---|---|---|
| N | 188 | 113 | 49 | 145 | 93 |
| Female sex, % (n) | 75 (140) | 68 (77) | 70 (34) | 73 (106) | 70 (65) |
| Ageb, mean (s.d.), years | 75.6 (9.9) | 75.3 (8.8) | 74.4 (7.8) | 76.6 (8.7) | 74.5 (9.8) |
| Ongoing glucocorticoid treatment at review, % (n) | 50 (94) | 51 (58) | 43 (21) | 52 (76) | 38 (35) |
| Documented depression, % (n) | 37 (69) | 38 (43) | 33 (16) | 41 (59) | 38 (35) |
| Documented significant weight loss, % (n) | 28 (53) | 27 (31) | 18 (9) | 33 (48) | 30 (28) |
| Elevated ESR or CRPb, % (n) | 90 (169) | 98 (111) | 100 (49) | 92 (133) | 91 (85) |
| ESRb, mean (s.d.), mm in first hour | 62 (26) | 60 (26) | 60 (29) | 63 (27) | 61 (21) |
| CRPb, median (IQR), mg/l | 58 (44–92) | 57 (34–87) | 57 (32–92) | 58 (35–93) | 57 (34–80) |
| RF positive, % (n/N) | 2 (4/42) | 0 (0/25) | 0 (0/24) | 2 (3/35) | 0 (0/24) |
| Anti-CCP positive, % (n/N) | 0 (0/29) | 0 (0/16) | 0 (0/17) | 0 (0/21) | 0 (0/16) |
| Rapid response to cortisone, valid % (n) | 44 (82) | 52 (59) | 66 (55) | 45 (65) | 70 (65) |
| Symptomatic response to cortisone, valid % (n) | 89 (167) | 97 (109) | 98 (45) | 90 (130) | 93 (86) |
Values are expressed as the total percentage unless otherwise indicated.
Missing data (all): elevated ESR/CRP at onset, n = 3; ESR at inclusion, n = 31; CRP at inclusion, n = 27; cortisone rapid response, n = 31; cortisone symptomatic response, n = 1.
a
By an expert in rheumatology in an independent review.
b
At onset of PMR.
IQR = interquartile range.