Table 2. Adjusted HRs for lipid disorders associated with gestational age at birth, Sweden, 1973–2016.
Gestational age at birth | Cases | Ratea | Unadjusted | Adjusted for child characteristicsb | Adjusted for child and maternal characteristicsc | |||
---|---|---|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |||
Preterm (<37 wks) | 1,426 | 101.89 | 1.32 (1.25–1.40) | <0.001 | 1.29 (1.22–1.36) | <0.001 | 1.23 (1.16–1.29) | <0.001 |
Extremely preterm (22–27 wks) | 31 | 148.78 | 2.24 (1.57–3.18) | <0.001 | 2.11 (1.49–3.01) | <0.001 | 2.00 (1.41–2.85) | <0.001 |
Very preterm (28–33 wks) | 301 | 111.64 | 1.47 (1.31–1.64) | <0.001 | 1.42 (1.26–1.59) | <0.001 | 1.33 (1.19–1.49) | <0.001 |
Late preterm (34–36 wks) | 1,094 | 98.63 | 1.27 (1.20–1.36) | <0.001 | 1.24 (1.17–1.32) | <0.001 | 1.19 (1.12–1.26) | <0.001 |
Early term (37–38 wks) | 4,187 | 85.99 | 1.15 (1.11–1.19) | <0.001 | 1.11 (1.08–1.15) | <0.001 | 1.09 (1.05–1.13) | <0.001 |
Full term (39–41 wks) | 16,712 | 80.12 | Reference | Reference | Reference | |||
Post term (≥42 wks) | 2,725 | 87.04 | 0.96 (0.93–1.00) | 0.08 | 1.00 (0.96–1.04) | 0.93 | 0.99 (0.95–1.03) | 0.62 |
Per additional 5 weeks (trend) | 0.80 (0.77–0.82) | <0.001 | 0.83 (0.81–0.86) | <0.001 | 0.86 (0.83–0.89) | <0.001 |
aIncidence rate per 100,000 person-years.
bAdjusted for birth year, sex, and birth order.
cAdjusted for birth year, sex, birth order, and maternal characteristics (age, education, birth country or region, body mass index, history of lipid disorder).
Abbreviations: HR, hazard ratio