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. 2019 Oct 18;16(10):e1002947. doi: 10.1371/journal.pmed.1002947

Table 3. Co-sibling analyses for gestational age at birth in relation to risk of lipid disorders, Sweden, 1973–2016.

Gestational age at birth Cases Ratea' Adjusted for shared familial factorsb Additionally adjusted for child and maternal characteristicsc
HR (95% CI) P HR (95% CI) P
Preterm (<37 wks) 1,006 93.86 1.14 (1.01–1.28) 0.03 1.10 (0.97–1.24) 0.13
    Extremely preterm (22–27 wks) 19 123.62 1.61 (0.75–3.45) 0.22 1.46 (0.68–3.15) 0.33
    Very preterm (28–33 wks) 203 101.91 1.15 (0.90–1.48) 0.25 1.09 (0.85–1.40) 0.49
    Late preterm (34–36 wks) 784 91.45 1.12 (0.99–1.28) 0.08 1.09 (0.96–1.24) 0.19
Early term (37–38 wks) 3,077 78.97 1.10 (1.03–1.18) 0.005 1.06 (0.98–1.13) 0.13
Full term (39–41 wks) 12,413 74.31 Reference Reference
Post term (≥42 wks) 2,004 82.57 0.97 (0.89–1.05) 0.41 1.02 (0.93–1.11) 0.69
Per additional 5 weeks (trend) 0.86 (0.80–0.93) <0.001 0.93 (0.86–1.00) 0.05

aIncidence rate per 100,000 person-years.

bAdjusted for shared familial (genetic and/or environmental) factors.

cAdditionally adjusted for specific child characteristics (birth year, sex, birth order) and maternal characteristics (age, education, birth country or region, body mass index, history of lipid disorder).

Abbreviations: HR, hazard ratio