Figure 3. Using triglycerides (TG):high-density lipoprotein cholesterol (HDL-c) ratio values in sickle cell anemia (SCA) patients to identify individuals with acute chest syndrome (ACS) and/or vaso-occlusive episodes (VOE). A, TG/HDL-c values were compared between the ACS+VOE group and controls using the Mann-Whitney U test. Lines represent median values and interquartile ranges. B, Receiver operator characteristics (ROC) curve analysis was employed to test the accuracy of TG/HDL-c values to discriminate between individuals with ACS+VOE history and controls. C, Detailed information obtained from the ROC curve, such as area under curves (AUC), P value of the ROC curves, cut-off value, and sensitivity and specificity with the 95% confidence interval (CI).
