Table III.
Clinical and demographic characteristics of women from whose neonates umbilical cord blood was obtained for in vitro studies.
| TB (n=6) | PTL PTB (n=9) | PTL PTB IAI (n=5) | p-value | |
|---|---|---|---|---|
| Maternal age (years; median [IQR])a | 23.5 (22.3–24.8) | 26 (23–27) | 24 (21–25) | 0.3 |
| Body mass index (kg/m2; median [IQR])a | 29.8 (23.3–34.9) | 21.7 (20–24.2) | 28.6 (23.3–32.5)c | 0.08 |
| Primiparityb | 50% (3/6) | 22.2% (2/9) | 40% (2/5) | 0.5 |
| Raceb | 0.7 | |||
| African-American | 83.3% (5/6) | 88.9% (8/9) | 80% (4/5) | |
| Caucasian | 16.7% (1/6) | 0% (0/9) | 20% (1/5) | |
| Other | 0% (0/6) | 11.1% (1/9) | 0% (0/5) | |
| Gestational age at Amniocentesis (weeks; median [IQR])a | 40.5 (40.3–40.6) | 33.3 (31.1–33.6) | 30.3 (26–32.6) | 0.05 |
| IL-6 (ng/mL; median [IQR])a | 2.1 (1.9–30.5) | 0.3 (0.2–0.5)c | 17.7 (16.8–67.1) | 0.002 |
| Gestational age at delivery (weeks; median [IQR])a | 40.5 (40.3–40.6) | 35.4 (33.7–36.3) | 31.9 (26.1–32.6) | 0.001 |
| Cesarean sectionb | 83.3% (5/6) | 44.4% (4/9) | 20% (1/5) | 0.1 |
| Birthweight (grams)a | 3342.5 (3070–3465) | 2585 (1860–2640) | 1955 (1040–2120) | 0.003 |
| Maternal inflammatory response (moderate/severe acute chorioamnionitis)b | 33.3% (2/6) | 33.3% (3/9) | 25% (1/4)c | 1 |
| Fetal inflammatory response (moderate/severe acute funisitis)b | 16.7% (1/6) | 0% (0/9) | 0% (0/4)c | 0.5 |
Data are given as median (interquartile range, IQR) and percentage (n/N). TB = term labor and birth; PTL PTB = preterm labor and birth; PTL PTB IAI = preterm labor and birth with intra-amniotic inflammation.
a
Kruskal-Wallis test.
b
Fisher’s exact test.
c
One missing data.