Table 1.
Baseline Characteristics in Studies One and Two
| Variable | Study One | Study Two |
|---|---|---|
| Age, y | 57.0 (10.2) | 69.2 (10.9) |
| Male sex | 25 (69.4%) | 247 (61.9%) |
| Systolic BP, mmlHg | 192.7 (42.5) | 176.1 (28.8) |
| Diastolic BP, mmlHg | 110 (24.9) | 93.6 (17.6) |
| Serum creatinine, μmol/L* | N/A | 77.6 (27.4) |
| Baseline NIHSS, median (IQR) | 23.0 (1.0–37.0) | 15.0 (11.0–19.0) |
| Smoker | N/A | 57 (14.3%) |
| DM | 10 (28.7%) | 65 (16.3%) |
| AF | 3 (8.3%) | 36 (9.0%) |
| Hypertension | 29 (80.6%) | 293 (73.4%) |
| Ml | 4 (11.1%) | 17 (4.3%) |
| Previous stroke | 3 (8.3%) | 90 (22.6%) |
| ↑cholesterol | N/A | 50 (12.5%) |
| ICH location | ||
| Deep | 33 (91.7%) | 343 (86.0%) |
| Lobar | 2 (5.6%) | 54 (13.5%) |
| Posterior Fossa | 0 (0.0%) | 1 (0.0%) |
| Primary IVH | 1 (2.8%) | 1 (0.0%) |
| ICH Volume, cm3 | 3.7 (0.8–12.6) | 16.4 (9.9–41.2) |
| Graeb Score, median (IQR) | 20 (16–32) | 6 (3–11) |
For continuous variables, values are expressed as mean (standard deviation) unless stated. For dichotomous variables, values are n (%). AF indicates atrial fibrillation; BP, blood pressure; DM, diabetes mellitus; ICH, intracerebral hemorrhage; IQR, interquartile range; IVH, intraventricular hemorrhage; MI, previous myocardial infarction; and NIHSS, National Institutes of Health Stroke Scale. N/A = not available in CLEAR B dataset. P values are for t test, Mann–Whitney tests or χ2 comparison.
*
Not available for 73 patients in VISTA analysis.