Table 2.
Overall associations of alcohol consumption with postmenopausal breast densitya
| N | Percent density (β and 95% CI) |
Absolute dense area (β and 95% CI) |
Non-dense area (β and 95% CI) |
|
|---|---|---|---|---|
| Alcohol use at mammogram | ||||
| 0 | 764 | Ref | Ref | Ref |
| 0–<5 | 707 | −0.06 (−0.22; 0.09) | 0.00 (−0.25; 0.25) | 0.11 (−0.19; 0.41) |
| ≥5 | 611 | 0.06 (−0.11; 0.22) | −0.08 (−0.34; 0.19) | −0.41 (−0.73; −0.09) |
| P for trend | 2082 | 0.32 | 0.53 | <0.01 |
| Continuous, per 10g | 2082 | 0.02 (−0.06; 0.09) | −0.08 (−0.20; 0.04) | −0.21 (−0.35; −0.06) |
a
Adjusted for age (continuous), BMI (continuous), age at menarche (<12, 12, 13, >13), a family history of breast cancer (Yes/No), a history of benign breast disease (Yes/No), NHS cohort (NHSI, NHSII), postmenopausal hormone use status (none, past, current, past/unknown current), age at menopause (<46, 46-<50, 50-<55, ≥55, unknown), and parity and age at first child’s birth (nulliparous, parous with age at first birth <25, parous with age at first birth ≥25)