TABLE II.
PWS total |
PWS deletion type I |
PWS deletion type II |
PWS UPD |
||||||
---|---|---|---|---|---|---|---|---|---|
Variables | N | Mean±SD | N | Mean±SD | N | Mean±SD | N | Mean±SD | P-value |
Age (years) | 24 | 26.5±8.7 | 8 | 26.8±4.1 | 6 | 26.7±11.5 | 10 | 26.2±10.3 | 0.989* |
BMI (kg/m2) | 24 | 35.0±9.0 | 8 | 35.2±9.6 | 6 | 36.3±9.3 | 10 | 34.0±9.1 | 0.889* |
FSH (mIU/ml) | 24 | 13.4±14.8 | 8 | 12.3±11.0 | 6 | 27.1±22.0 | 10 | 7.0±4.9 | 0.010** |
LH (mIU/ml) | 24 | 2.9±2.4 | 8 | 1.7±2.0 | 6 | 4.9±3.3 | 10 | 2.6±1.1 | 0.019** |
Testosterone (ng/ml) | 23 | 1.5±1.4 | 8 | 1.1±1.0 | 5 | 1.4±1.6 | 10 | 1.9±1.7 | 0.543** |
Normal reference range: follicular stimulating hormone (FSH) for ≥16-year-old males—0.7–11.1 mIU/ml; lutenizing hormone (LH) for ≥16-year-old males—0.8–7.6 mIU/ml; testosterone for ≥16-year-old males—2.45–18.4 ng/ml.
P-values calculated by using one-way ANOVA.
P-values calculated by using univariate analysis among all three genetic subtype groups (deletion type I, deletion type II and UPD) adjusting for age and BMI.