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. Author manuscript; available in PMC: 2019 Oct 18.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2018 May 17;134:7–16. doi: 10.1016/j.plefa.2018.05.001

Table 3. Evaluation of analyte standardization approach variance minimization using the chi-square (χ2) statistic.

The variance in each of the 58 reported analytes processed through the four standardization factors were compared, with the per Sebutape® standardization set as the reference. If equivalent, 50% of analytes would have a lower %CV than the reference approach.

Standardizing Factor AD Control


n > 1 (%)a χ2 P n > 1 (%)a χ2 P
Sebumeter® reading 48 (83%) 12.45 0.0004 48 (83%) 12.45 0.0004
Total TFA 51 (88%) 16.69 0.00004 22 (38%) 1.69 0.2
Total NEFA 49 (84%) 13.79 0.0002 37 (64%) 2.21 0.1
a

The number (and percentage) of reported analytes with variance greater than the reference per Sebutape® standardization approach.