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. Author manuscript; available in PMC: 2019 Oct 18.
Published in final edited form as: Bone. 2019 Jan 31;121:221–226. doi: 10.1016/j.bone.2019.01.026

Figure 1.

Figure 1.

Sp1 variant in COLIA1 affects bone density prior to and during puberty in females. aBMD and BMC age, sex, and population ancestry-specific Z-scores were calculated and further adjusted for height-for-age Z-scores. A. Main effects by genotype for lumbar spine and femoral neck aBMD Z-scores. B. Puberty interactions by genotype for lumbar spine and femoral neck aBMD Z-scores. T1, Tanner stage 1 (pre-pubertal); T2-T4, Tanner stages 2 to 4 (pubertal); T5, Tanner stage 5 (post-pubertal). P-values in column A are for the main variant associations; P-values in column B are for the variant-puberty stage interactions. TBLH, total body less head.