Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 1;26(10):915–930. doi: 10.5551/jat.48405

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2019 Japan Atherosclerosis Society

This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License.http://creativecommons.org/licenses/by-nc-sa/3.0/

PMC Copyright notice

Fig. 3. — Effects of rivaroxaban on atherosclerosis in the aortic root and on occluded coronary arteries in ICM model mice

Rivaroxaban alleviated atherosclerosis and occluded coronary arteries in ICM model mice.

(A) Representative images of oil red O staining of atherosclerotic plaques in aortic roots. Rivaroxaban treatment alleviated lipid deposition as compared with the non-treated group (n = 5–7; bar = 500 µm). (B) HE staining indicated that occluded coronary arteries were decreased by rivaroxaban treatment compared with the non-treated group (n = 11–14; bar = 50 µm). (C) The mRNA expression of proinflammatory genes revealed that rivaroxaban decreased the inflammatory molecules in the heart (n = 8–9). *p < 0.05, **p < 0.01, and ***p < 0.001.