Table 3. Procedural characteristics of STEMI patients according to median baseline serum SFRP5 level.
Variables | Total (N = 85) | Low-SFRP5 Group (N = 42) | High-SFRP5 Group (N = 43) | P value |
---|---|---|---|---|
Angiography | ||||
No. of diseased vessels | 0.443 | |||
1-vessel disease | 45 (52.9) | 22 (52.4) | 23 (53.5) | |
2-vessel disease | 22 (25.9) | 9 (21.4) | 13 (30.2) | |
3-vessel disease | 18 (21.2) | 11 (26.2) | 7 (16.3) | |
Location of culprit lesion | 0.952 | |||
Proximal LAD | 32 (37.6) | 16 (38.1) | 16 (37.2) | |
Middle LAD | 44 (51.8) | 21 (50.5) | 23 (53.5) | |
Distal LAD | 9 (10.6) | 5 (11.9) | 4 (9.3) | |
Pre-PCI TIMI flow | 0.346 | |||
Grade 0 | 72 (84.7) | 33 (78.6) | 39 (90.7) | |
Grade 1 | 10 (11.8) | 7 (16.7) | 3 (7.0) | |
Grade 2 | 3 (3.5) | 2 (4.8) | 1 (2.3) | |
Grade 3 | 0 | - | - | |
Intervention therapy | ||||
Total ischemic time (min) | 278 (194, 413) | 322 (200, 553) | 271 (190, 408) | 0.399 |
Stent implantation | 84 (98.8) | 42 (100) | 42 (97.7) | 1.000 |
2nd-generation DES | 84 (98.8) | 42 (100) | 42 (97.7) | 1.000 |
No. of stents per patient | 1.11 ± 0.31 | 1.10 ± 0.30 | 1.12 ± 0.33 | 1.000 |
No. of stent diameter ≤ 2.5 mm | 5 (5.9) | 3 (7.1) | 2 (4.7) | 0.676 |
Length of stent | 30 (24, 36) | 29 (25, 36) | 30 (24, 33) | 0.780 |
Thrombus aspiration | 9 (10.6) | 4 (9.5) | 5 (11.6) | 1.000 |
GP IIb/IIIa inhibitor | 54 (63.5) | 28 (66.7) | 26 (60.5) | 0.654 |
Post-PCI TIMI flow ≥ 2 | 78 (91.8) | 38 (90.5) | 40 (93.0) | 0.713 |
STEMI, ST-segment elevation myocardial infarction; SFRP5, serum secreted frizzled-related protein 5; LAD, left anterior descending; PCI, percutaneous coronary intervention; TIMI: thrombolysis in myocardial infarction; DES, drug eluting stent; GP IIb/IIIa: Glycoprotein IIb/IIIa.