Fig. 3.

Structural-decoupling index reveals organization according to a behaviorally relevant gradient. a NeuroSynth meta-analysis is applied to the decoupling index gradient; b similar analysis conducted in ref. ³⁰ on a functional connectivity gradient (right). Our analysis shows for the first time that the strength of structure–function coupling orders regions according to behavioral relevance, in accordance with other known principles of brain organization. In fact, despite the two analyses have a different input, a similar trend is found, correlating regions at one extreme of the gradient to lower-level sensory–motor functions and regions at the opposite extreme to higher-cognitive functions. The regions found at the extremes in ref. ³⁰ are highlighted in both diagrams. Source data to reproduce a are provided as a Source Data file. b Adapted with permission from Fig. 4 in ref. ³⁰