Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Simulated steady-state tapentadol area under the curve in adult subjects receiving tapentadol every 4 hrs for 5 days
| Dose (mg) | Simulated median steady-state AUC (ng· h/mL) | ||
|---|---|---|---|
| 2.5% Percentile | Median | 97.5% Percentile | |
| 50 | 130.7 | 216.8 | 353.0 |
| 75 | 196.1 | 325.3 | 529.0 |
| 100 | 261.5 | 433.5 | 706.0 |
Abbreviation: AUC, area under the curve.
