Table 1.
Baseline clinical characteristics of the study population
| Variable | Non-DM (n = 184) | Short-DM (n = 64) | Long-DM (n = 31) | P value | PNon vs. Short | PShort vs. Long | PNon vs. Long |
|---|---|---|---|---|---|---|---|
| Age, years | 57.5 ± 11.6 | 55.2 ± 11.5 | 61.0 ± 10.5 | 0.063 | |||
| BMI, kg/m2 | 25.8 ± 4.0 | 27.1 ± 3.4 | 26.1 ± 2.8 | 0.072 | |||
| Men | 152 (82.6) | 50 (78.1) | 27 (87.1) | 0.586 | |||
| Smoking | 127 (69.0) | 43 (67.2) | 24 (77.4) | 0.623 | |||
| Medical history | |||||||
| Hypertension | 102 (55.4) | 41 (64.1) | 20 (64.5) | 0.378 | |||
| Dyslipidemia | 168 (91.3) | 56 (87.5) | 29 (93.5) | 0.630 | |||
| Prior PCI | 12 (6.5) | 5 (7.8) | 4 (12.9) | 0.388 | |||
| Laboratory findings | |||||||
| White blood cell count, × 106/L | 10.6 ± 3.2 | 10.9 ± 3.2 | 10.0 ± 2.7 | 0.624 | |||
| Hs-CRP, mg/L | 5.3 (2.4, 10.9) | 6.6 (2.9, 10.3) | 4.0 (2.6, 10.6) | 0.840 | |||
| eGFR, mL/min/1.73 m2 | 97.3 (77.7, 114.3) | 99.9 (88.2, 119.1) | 93.2 (77.8, 107.3) | 0.119 | |||
| HbA1c, % | 5.7 (5.5, 5.9) | 7.6 (6.8, 8.9) | 8.4 (7.7, 9.8) | < 0.001* | < 0.001* | 0.001* | < 0.001* |
| TC, mg/dL | 164.0 (139.2, 195.2) | 172.1 (155.8, 203.2) | 175.9 (130.7, 205.0) | 0.172 | |||
| TG, mg/dL | 114.7 (73.7, 167.8) | 154.5 (104, 215.8) | 144.3 (90.3, 206.3) | 0.001* | 0.006* | 0.996 | 0.046 |
| LDL-C, mg/dL | 104 (82.6, 127.5) | 114.5 (95.3, 133.0) | 103.6 (78.9,128.4) | 0.279 | |||
| HDL-C, mg/dL | 41.4 (35.6, 48.3) | 39.3 (35.3, 45.7) | 39.8 (34.8, 47.6) | 0.417 | |||
| Lipoprotein (a), mg/L | 179.8 (84.5, 393) | 107.5 (49,311.4) | 149.0 (87.1, 315.0) | 0.825 | |||
| LVEF, % | 54.7 ± 6.5 | 56.6 ± 5.2 | 53.9 ± 5.4 | 0.062 | |||
| Prior medications | |||||||
| Aspirin | 64 (34.8) | 29 (45.3) | 12 (38.7) | 0.310 | |||
| P2Y12 inhibitor | 43 (23.4) | 17 (26.6) | 11 (35.5) | 0.323 | |||
| Statin | 34 (18.5) | 8 (12.5) | 5 (16.1) | 0.592 | |||
| DM control | |||||||
| Insulin | 5 (7.8) | 11 (35.5) | |||||
| Oral hypoglycemic agents | 40 (62.5) | 18 (58.1) | |||||
| Diet only | 19 (29.7) | 2 (6.5) | |||||
Continuous data are presented as mean ± standard deviation or median (25th, 75th percentile). Categorical data are presented as number (%)
BMI body mass index, DM diabetes mellitus, eGFR estimated glomerular filtration rate, HbA1c glycosylated hemoglobin, HDL-C high-density lipoprotein cholesterol, Hs-CRP high-sensitivity C-reactive protein, PCI percutaneous coronary intervention, LDL-C low-density lipoprotein cholesterol, Long-DM patients with a long duration of diabetes, LVEF left ventricular ejection fraction, Non-DM patients without diabetes, Short-DM patients with a short duration of diabetes, TC total cholesterol, TG triglyceride
* P < 0.05