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Activation of FXN protein expression, western analysis. (A) FXN protein in FRDA patient-derived NPCs F4259 and wild-type NPCs C7522 (n = 3) with different confluency. (B) FXN protein expression in FRDA patient-derived NPCs F4259 when transfected with oligonucleotides (5 µM) using Optimization 4 (n = 3) post 96 h transfection. All data are presented as ±STDEV. (*) P < 0.05, (**) P < 0.01, (***) P < 0.001, relative to F4259-90% by Student t-test.
