Figure 2. Principal components for the citalopram conditions.

Mean ± standard error for (A) locomotion (B) behavioral anxiety, and (C) positional anxiety, over 6-min trials, showing overall variation, as well as for each concentration of citalopram (control 0, 30, 50, and 100 mg/L) based on the reconstructed trajectories in 3D. Data were analyzed through a repeated measures ANOVA for split-plot designs. Filled symbols denote a significant difference (P < 0.05) from the first minute within each condition. Horizontal bar denotes a significant overall difference in time.