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CaHA particle (1 m) in Figure 5 with 400× magnification. The large size particle was likely injected recently and particle might be injected 1 month before the biopsy. The particle was not surrounded by giant cells or macrophages (Mp), only fibroblasts (*) as shown here. This CaHA particle (1 m) was surrounded by five fibroblasts, which may have contributed newly made thin collagen fibers (Cf), even at 1 month post injection.
