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. 2019 Oct 15;12:771–784. doi: 10.2147/CCID.S212599

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© 2019 Kim.

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Type III Collagen antibody stain (100×) in the same area of Figure 11,12,14. Collagen-III fibers (3) appeared brown around and between particles (1 m, 7 m) in the dermis. The shape was in various thicknesses, from thick and densely stained Collagen-III to very thin Collagen-III fibers. Abundant type-III collagen was observed even 7 months after injection of CaHA filler and this is very first finding. This means new collagen (Type II I and I both) was created continually if CaHA particle existed. Abundant FGCs (stained light blue) and its nuclei (dark blue) observed around smaller CaHA particles in Type-III collagen antibody stain.