Table 2.
Proteins with significantly altered levels in neuropathic pain patients
| Gene | Protein | Antibody | p-value | Adj. p-value | Fold change |
|---|---|---|---|---|---|
| APOC1 | Apolipoprotein-C1 | HPA051518 | 0.00001 | 0.0001 | 1.1 |
| CHGB | Secretogranin 1 | HPA012602 | 0.0003 | 0.01 | 0.1 |
| NRXN1 | Neurexin-1 | HPA059963 | 0.00001 | 0.0001 | -0.3 |
| APOA1 | Apolipoprotein-A1 | HPA046715 | 0.00001 | 0.0001 | -0.6 |
| DKK3 | Dickkopf related protein 3 | HPA011164 | 0.0001 | 0.001 | -0.3 |
| SOD1 | Superoxide dismutase 1 | HPA001401 | 0.0001 | 0.001 | -0.8 |
| CFH | complement factor H | HPA053326 | 0.0007 | 0.01 | -0.2 |
| PTGDS | Prostaglandin | HPA004938 | 0.001 | 0.01 | -0.2 |
| C7 | complement component C7 | HPA067450 | 0.002 | 0.01 | -0.3 |
| HPX | Hemopexin | HPA068847 | 0.004 | 0.01 | -0.3 |
Notes: Proteins with altered CSF levels between patients and controls in stage 1 comparing NP1 to C1.