Figure 2.
The comparison of the proposed method with T1 and T2 mapping by standard parameter mapping methods (i.e., IR-FSE and CPMG) on six Sprague Dawley rats (N = 6 with two normal controls and four with chronic ischemic lesions in the left hemisphere, all images and analysis are presented in Supporting Figure 1). There is a strong spatial agreement between the methods. The differences/errors (mean difference ± standard deviation of difference) in two Bland Altman plots were 113 ± 486 and 154 ± 512 ms for T1, and 5 ± 33 and 7 ± 41 ms for T2, respectively. The on average shorter T1 and T2 values resulting from IR-bSSFP with neural network processing can be attributed to magnetization transfer effects31–33.
