Table 1.
Behavioral Test | Comparisons | ||
---|---|---|---|
IL-6 tg+/+ vs IL-6 tg −/− | IL-6 tg+/+ vs IL-6 tg +/− | IL-6 tg+/− vs IL-6 tg −/− | |
1. Light/Dark Transfer | |||
- time spent in light chamber | ns | ns | ns |
- # of transitions | ↓ | ↓ | ns |
2. Open field test | |||
- distance | ↓ | ↓ | ns |
- velocity | ↓ | ↓ | ns |
- center entries | ↓ | ↓ | ns |
- center time | ns | ns | ns |
3. Grooming, rearings | ns | ns | ns |
4. Digging bouts | ↓ | ↓ | ns |
5. Tail suspension test | ns | ns | ns |
6. Forced swim test | |||
Immobility | ↑ | ↑ | ns |
7. HIC score | ↑ | ↑ | ns |
↓= decrease, ↑= increase; ns = no significant difference