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. Author manuscript; available in PMC: 2020 Oct 16.
Published in final edited form as: Bioconjug Chem. 2019 Sep 27;30(10):2528–2532. doi: 10.1021/acs.bioconjchem.9b00524

Figure 1.

Figure 1.

Fluorescent images of T98G cells treated with D-1 for 2 h and then following by (A) Hoechst 33342 staining; (B) immunofluorescence of fibrillarin (abcam, ab5821); (C) ER Tracker staining. Scale bar is 10 μm. (D) TEM and (E) the corresponding confocal laser scanning microscopy (CLSM) images of D-1, and D-1 plus the RNA extracted from T98G cells. All the compounds are dissolved in PBS buffer (final pH=7.4) at concentration of 200 μM. Scale bar in TEM is 100 nm, and 5 μm in CLSM. For better comparing, we changed the color of the Hoechst 33342 to red.