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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Anesth Analg. 2019 Nov;129(5):1365–1373. doi: 10.1213/ANE.0000000000004418

Figure 6. BDNF mRNA levels in the cortex and hippocampus of animals after perinatal isoflurane exposure.

Figure 6

A./C. P21 (time of weaning) relative levels of BDNF mRNA in cortex and hippocampus respectively, displayed as fold change. Neither brain region was significantly different (Cortex (n=5) p=0.222, Hippocampus (n=5) p=0.547, Unpaired two-tailed Mann-Whitney test). B./D. P43 (3 weeks of +/− exercise) relative levels of BDNF mRNA in cortex and hippocampus respectively. Unlike BrdU incorporation, there was no significant effect of exercise (Con/Sedentary n=8, Con/Exercise n=9, Iso/Sedentary n=10, Iso/Exercise n=10); ; Cortex two-way ANOVA F(1,32) =0.236 p=0.631; Hippocampus two-way ANOVA F (1,33) =1.186 p=0.284.

Geometric mean and 95% confidence intervals displayed.