Table 2:

Demographic and Clinical Factors for Mycophenolate Patient Group

Genotype		rs4149117			rs7311358
		GG (n=164)	TT/GT (n=54)	p	AA (n=166)	GG/AG (n=51)	p
Recipient Factors	Age (years, mean ±SD)	53.2±13.7	53.2±12.4	0.978	53.2±13.7	53.4±12.4	0.932
	Female Gender, n (%)	61 (37.2)	28 (51.9)	0.057	62 (37.3)	27 (52.9)	0.048
	Race, n (%)						0.026
	White	158 (96.3)	47 (87)	0.012	160 (96.4)	45 (88.2)
	Non-White	6(3.7)	7(13)		6(3.6)	6 (11.8)
	Diagnosis, n (%)			0.310			0.448
	ILD	81 (49.4)	23 (42.6)		81 (48.8)	23 (45.1)
	COPD	35 (21.3)	15 (27.8)		36 (21.7)	14 (27.5)
	Cystic Fibrosis	27 (16.5)	9 (16.7)		28 (16.9)	8 (15.7)
	A1AT	7(4.3)	0 (0)		7 (4.2)	0 (0)
	Sarcoidosis	3 (1.8)	3 (5.6)		3 (1.8)	2 (3.9)
	Other	10 (6)	3(5.6)		10 (6)	3 (5.9)
	LAS	48.4±19.6	49.3±20.4	0.779	48.3±19.5	49.9±20.7	0.601
Donor Factors	Age, years (mean ±SD)	37.0±14.2	37.1±16.1	0.968	36.9±14.2	37.1±16.3	0.931
	Female Gender, n (%)	59 (36)	20 (37)	0.888	60 (36.1)	18 (35.3)	0.912
	Race, n (%)			0.238			0.335
	White	124 (75.6)	45 (83.3)		126 (75.9)	42 (82.4)
	Non-White	40 (24.4)	9 (16.7)		40 (24.1)	9 (17.6)
Transplant Factors	Transplant Type			0.255			0.279
	Bilateral	156 (95.1)	54 (100)		158 (95.2)	51 (100)
	Single	8 (4.8)	0 (0)		8 (4.9)	0 (0)
	Cardiopulmonary Bypass	81 (49.4)	33 (61.1)	0.135	81 (48.8)	32 (62.7)	0.081
	Ischemic Time, min (mean ± SD)	275.6±68.1	283.6±72.5	0.466	276.4±68	279.2±71.8	0.793
	PGD at 72 hours			0.440			0.624
	0	30 (19.1)	14 (26.9)		32 (20.1)	12 (24.5)
	1	108 (68.8)	32 (61.5)		108 (67.9)	31 (63.3)
	2	11 (7.0)	5 (9.6)		11 (6.9)	5 (10.2)
	3	8 (5.1)	1 (1.9)		8 (5.0)	1 (2.0)
	Calcineurin Inhibitor			0.956			0.885
	Tacrolimus	159 (96.9)	54 (100%)		161 (97)	51 (100)
	Cyclosporine	5 (3.1)	0		5 (3)	0
	Any Acute Rejection at 1 Year, n (%)	126 (76.8)	36 (66.7)	0.138	127 (76.5)	35 (68.6)	0.258
	MPA Dose, g [median(range)]
	Month 1	1 (0–3)	1.25 (0–2.5)	0.167	1 (0–3)	750 (0–1.5)	0.134
	Month 6	1 (0–3)	1 (0–2)	0.171	1 (0–3)	1 (0–2)	0.287
	Month 12	1 (0–3)	1 (0–2)	0.345	1 (0–3)	1 (0–3)	0.549

ILD: Interstitial lung disease, COPD: chronic obstructive pulmonary disease, A1AT: alpha-1 antitrypsin, LAS: lung allocation score, PGD: primary graft dysfunction