Table 4:

Cox Regression Analysis for Risk of Death by Genotype in Patients Receiving Mycophenolic Acid

rs7311358
	Risk of Death at One Year			Risk of Death at Three Years
Overall Model	Chi-square 22.082 p=0.002			Chi-square 11.298 p=0.080
Variable	Hazard Ratio	95% CI	p-value	Hazard Ratio		95% CI	p-value
Recipient Gender	1.74	0.30–9.97	0.535	1.38		0.75–2.55	0.303
Recipient Race, Nonwhite	2.74	0.27–27.34	0.391	2.02		0.71–5.75	0.190
Donor Race, Nonwhite	3.72	0.69–20.10	0.127	1.53		0.80–2.90	0.197
Cardiopulmonary Bypass	0.62	0.11–3.42	0583	0.63		0.35–1.14	0.129
No Acute Rejection at 1 year	0.17	0.03–0.90	0.037	--		--	--
rs7311358: GG or GA	7.76	1.37–44.04	0.021	1.97		1.04–3.72	0.036
CNI: Cyclosporine vs. tacrolimus	12.73	0.83–19.49	0.068	2.41		0.56–10.48	0.239
rs4149117
	Risk of Death at One Year			Risk of Death at Three Years
Overall Model	Chi-square 20.993 p=0.004			Chi-square 8.564 p=0.128
Variable	Hazard Ratio	95% CI	p-value	Hazard Ratio	95% CI		p-value
Recipient Gender	1.63	0.29–9.12	0.586	1.36	0.74–2.51		0.318
Recipient Race, Nonwhite	2.22	0.22–22.26	0.498	--	--		--
Donor Race, Nonwhite	4.08	0.75–22.17	0.103	1.51	0.79–2.87		0.205
Cardiopulmonary Bypass	0.62	0.11–3.38	0.576	0.67	0.38–1.20		0.181
No Acute Rejection at 1 year	0.18	0.04–0.96	0.045	--	--		--
rs4149117: TT or TG	7.28	1.27–41.78	0.026	1.86	0.99–3.48		0.054
CNI: Cyclosporine vs. tacrolimus	12.28	0.83–182.69	0.069	2.23	0.53–9.95		0.265