Table 2.
Comparison of fibrin clot properties
| Variable | Total cohort (n = 186) | Patients with venous ulcer (n = 12) | Patients free of venous ulcer (n = 174) | P |
|---|---|---|---|---|
| Ks, 10−9 cm2 | 7.45 ± 1.27 | 6.53 ± 0.45 | 7.51 ± 1.28 | < 0.001 |
| CLT (min) | 88 (72–100) | 101 (88–114) | 86 (72–99) | 0.007 |
| Lag phase (s) | 41 (37–46) | 36.5 (35–39.75) | 42 (38–46) | 0.003 |
| ΔAbs (405 nm) | 0.81 (0.75–0.86) | 0.84 (0.81–0.9) | 0.8 (0.74–0.86) | 0.03 |
| D-Dmax (mg/L) | 3.99 (3.60–4.39) | 3.68 (3.59–3.99) | 4.07 (3.6–4.39) | 0.132 |
| D-Drate (mg/L/min) | 0.072 ± 0.008 | 0.072 ± 0.009 | 0.072 ± 0.008 | 0.68 |
Values are given as mean ± SD or a median (interquartile range)
Ks indicates permeability coefficient; CLT clot lysis time, ΔAbs maximum absorbance, D-Dmax maximum D-dimer levels in the lysis assay, and D-Drate maximum rate of increase in D-dimer levels in the lysis assay