Table 2.
Adverse events
| n | (%) | i. a. chemotherapy | % | UAP | % | |
|---|---|---|---|---|---|---|
| 454 | 100 | 233 | 100 | 221 | 100 | |
| Bone marrow suppression grades 1–2 | 77 | 17 | 20 | 8.6 | 57 | 25.8 |
| Bone marrow suppression grades 3–4 (only patients with multiple lines of previous systemic chemotherapy) | 23 | 5 | 4 | 1.7 | 19 | 8.6 |
| Postoperative wound infection | 5 | 1 | 0 | 0 | 5 | 2.3 |
| Postoperative thrombosis | 5 | 1 | 0 | 0 | 5 | 2.3 |
| Temporary lymph fistula in the groin | 136 | 30 | 0 | 0 | 136 | 61.5 |
| Renal toxicity | 50 | 11 | 0 | 0 | 50 | 22.6 |
| Nausea grade 1 | 159 | 35 | 70 | 30 | 89 | 40.2 |
| Nausea grade 2 | 68 | 15 | 33 | 14 | 35 | 15.8 |
| Vomiting grade 2 | 45 | 10 | 21 | 9 | 24 | 10.9 |
| Diarrhea | 23 | 5 | 2 | 0.8 | 21 | 9.5 |
| Neurotoxicity (only patients with multiple lines of previous systemic chemotherapy) | 14 | 3 | 7 | 3 | 7 | 3.1 |
| Incomplete hair loss | 59 | 13 | 31 | 13.3 | 28 | 12.7 |
| Fatigue | 47 | 10.4 | 21 | 9 | 26 | 11.8 |