Fig. 1.

Distribution and density of Lewy-related pathology in the investigated brain regions. a, b Caudo-rostral n = 83 and c, d amygdala-based n = 40 progression patterns visualized (y-axis) by quantity (n) and percentage (%). Mean values (SD) of the investigated brain regions are shown in Supplemental Table 4. Spinal S = sacral spinal cord, spinal Th = thoracic spinal cord, sn = substantia nigra, amy = amygdala, ca2 = ca2 of hippocampus, tox = transentorhinal cortex of hippocampus, cing = cingulate cortex, temp = temporal cortex, front = frontal cortex, pariet = parietal cortex, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe Lewy-related pathology