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. 2019 Oct 15;12:8501–8513. doi: 10.2147/OTT.S208263

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© 2019 Lv et al.

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Resuming miR-761 expression restricts cell proliferation, migration, invasion and induces cell apoptosis in OS. (A) U2OS and HOS cells were treated with agomir-NC or agomir-761. RT-qPCR was applied for the determination of transfection efficiency. *P<0.05 vs agomir-NC. (B) The proliferation in miR-761 overexpressing-U2OS and HOS cells was evaluated by CCK-8 assay. *P<0.05 vs agomir-NC. (C) The proportion of apoptosis U2OS and HOS cells transfected with agomir-NC or agomir-761 was assessed via flow cytometry analysis. *P<0.05 vs agomir-NC. (D, E) The migration and invasion of agomir-NC or agomir-761-transfected U2OS and HOS cells was investigated using transwell migration and invasion assays. *P<0.05 vs agomir-NC.