Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 15;12:8501–8513. doi: 10.2147/OTT.S208263

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Lv et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Silencing FGFR1 expression inhibits the proliferation, migration, invasion and promotes the apoptosis of OS cells. si-FGFR1 or si-ctrl was transfected into U2OS and HOS cells. (A) The protein level of FGFR1 in U2OS and HOS cells after si-FGFR1 or si-ctrl transfection was assessed using Western blotting. *P<0.05 vs si-ctrl. (B, C) Cell proliferation and apoptosis in abovementioned cells was measured by CCK-8 assay and flow cytometry analysis. *P<0.05 vs si-ctrl. (D, E) Cell migration and invasion in FGFR1 decreasing-U2OS and HOS cells was determined by transwell migration and invasion assays. *P<0.05 vs si-ctrl.