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. 2019 Oct 15;12:8501–8513. doi: 10.2147/OTT.S208263

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© 2019 Lv et al.

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FGFR1 restoration counteracts the phenotype resulted from miR-761 overexpression in OS cells. (A) Western blotting was carried out to determine FGFR1 expression in U2OS and HOS cells that were co-transfected with agomir-761 and pCMV-FGFR1 or pCMV. *P<0.05 vs agomir-NC. **P<0.05 vs agomir-761+pCMV. (B, C) The proliferation and apoptosis of U2OS and HOS cells treated as above described was measured via CCK-8 assay and flow cytometry analysis. *P<0.05 vs agomir-NC. **P<0.05 vs agomir-761+pCMV. (D, E) Transwell migration and invasion assays were employed to detect the migratory and invasive abilities in aforementioned cells. *P<0.05 vs agomir-NC. **P<0.05 vs agomir-761+pCMV.