Table 2.
Variability of amino acid residues of the NS5B protein from HCV genotypes 1-7 at positions, in which the protein of JFH-1 isolate contains cysteine residues.
| Gt | Isolate | 14 | 39 | 89 | 146 | 170 | 223 | 243 | 274 | 279 | 295 | 303 | 316 | 366 | 521 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1a | H77 | C | S | C | C | C | C | C | C | C | C | C | C | C | C |
| TN | C | S | C | C | C | C | C | C | C | C | C | C | C | C | |
| HCV1 | C | S | C | C | C | C | C | C | C | C | C | C | C | C | |
|
| |||||||||||||||
| 1b | Con1 | C | A | C | C | C | C | C | C | C | C | C | C | C | C |
| J4 | C | A | C | C | C | C | C | C | C | C | C | N | C | C | |
| DH1 | C | A | C | C | C | C | C | C | C | C | C | C | C | C | |
|
| |||||||||||||||
| 2a | JFH1 | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| JFH2 | C | C | C | C | C | C | C | C | C | C | C | C | C | C | |
| J6 | C | C | C | C | C | C | C | C | C | C | C | C | C | C | |
|
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| 2b | J8 | C | S | C | C | C | C | C | C | C | C | C | C | C | C |
|
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| 3a | S52 | C | S | C | C | C | C | C | C | C | C | A | C | C | C |
|
| |||||||||||||||
| 4a | ED43 | C | A | C | A | C | C | C | C | C | C | I | C | C | C |
|
| |||||||||||||||
| 5a | SA13 | C | S | C | A | C | C | C | C | C | C | C | C | C | C |
|
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| 6a | EUHK2 | C | S | C | C | C | C | C | C | C | C | C | C | C | C |
|
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| 7a | QC69 | S | S | A | C | C | C | C | V | C | C | A | C | C | C |