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. 2019 Oct 17;7:e7815. doi: 10.7717/peerj.7815

Figure 5. Rosiglitazone administration increases the levels of VEGF and SDF-1α protein and improved insulin resistant in db/db mice.

Figure 5

(A) Effect of RSG treatment on SDF-1α protein levels in serum of the db/db mice. (B) ELISA analyses of VEGF levels in supernatant of BM-EPCs. (C) BM-EPCs treated with or without 1 µmol/L insulin for 1 h, and concentrations of phosphorylated AKT and total AKT were determined by the ELISA kit. Values are mean ± SEM, (A, B: n = 6; C: n = 5 per group). A, B: ∗P < 0.05 vs. Control; A, B: #P < 0.05 vs. db/db. RSG, rosiglitazone.