Table 3.
Results of core laboratory assessment for stenosis, qualitative high-risk plaque and quantitative plaque stratified by FFRCT results (per vessel analysis).
| FFRCT ≤0.80 n=71 | FFRCT >0.80 n=175 | p value | |
|---|---|---|---|
| Stenosis – no. (%) | |||
| Mild (<50%) | 37 (52.1) | 170 (97.1) | <0.001 |
| Moderate (50–69%) | 13 (18.3) | 4 (2.3) | <0.001 |
| Severe (≥70% or ≥50% LM) | 21 (29.6) | 1 (0.6) | <0.001 |
| Qualitative plaque – no. (%) | |||
| Any high-risk plaque | 48 (67.6) | 52 (29.7) | <0.001 |
| Positive remodeling | 23 (32.4) | 9 (5.1) | <0.001 |
| Low HU plaque | 15 (23.1) | 5 (2.9) | <0.001 |
| Napkin-ring sign | 13 (18.3) | 2 (1.1) | <0.001 |
| Spotty calcium | 41 (57.8) | 50 (28.6) | <0.001 |
| Quantitative plaque – mean ± SD | |||
| Total plaque volume, mm3 | 198.5 ± 188.8 | 43.2 ± 79.7 | <0.001 |
| Plaque Volume <30 HU, mm3 | 4.7 ± 7.6 | 1.1 ± 4.7 | <0.001 |
| Remodeling index | 1.24 ± 0.29 | 1.05 ± 0.14 | <0.001 |