Table 3:
Antibiotic Use in Subjects Becoming Culture Positive
| Subject | Time from CN to CP (months) |
Organism | Abx Prior to Initial I&D |
Duration of Abx Prior to initial I&D |
Abx After Initial I&D |
Duration of Abx After initial I&D |
|---|---|---|---|---|---|---|
| 1 | 18 | MRSA | Vancomycin | 10 days | Vancomycin | 6 weeks |
| 2 | 11 | Coag Negative Staph |
Amoxicillin- Clavulanic Acid |
>1 year | Cefepime/ Daptomycin |
6 weeks |
| 3 | 4 | MSSA | Vancomycin | 1-time bolus 4 days prior to I&D |
Keflex | 4 weeks |
| 4 | 23 | Coag Negative Staph |
None | Vancomycin/ rifampin; Bactrim |
6 weeks; ~4 months | |
| 5 | 9 | E. faecalis | None | Vancomycin/ Ceftriaxone |
6 weeks | |
| 6 | 10 | Alpha Hemolytic Strep |
None | Daptomycin; Bactrim |
6 weeks; ~4 months | |
| 7 | 1 | Coag Negative Staph |
None | Bactrim/ Ciprofloxacin |
3 weeks | |
| 8 | 2 | P. aeruginosa | None | Ciprofloxacin | 4 days |
Note: Subject two on suppressive antibiotic regimen for previous hip MRSA PJI.