Table 1.
PD-L1 expression: overall and by IMDC risk groups
METEOR (N=306) | CABOSUN (N=110) | |||
---|---|---|---|---|
N | N(%) with PD-L1(+) (≥1% cutoff for TC and IC) |
N | N(%) with PD-L1(+) (≥1% cutoff for TC and IC) |
|
Tumor cells | ||||
All patients | 306 | 88(29) | 110 | 25(23) |
By IMDC risk groups | ||||
Favorable | 64 | 11(17) | - | - |
Intermediate | 198 | 58(29) | 88 | 15(17) |
Poor | 44 | 19(43) | 22 | 10(45) |
P-value | 0.013 | 0.009 | ||
Immune cells | ||||
All patients | 301 | 179(59) | 110 | 67(61) |
By IMDC risk groups | ||||
Favorable | 61 | 28(46) | - | - |
Intermediate | 196 | 119(61) | 88 | 50(57) |
Poor | 44 | 32(73) | 22 | 17(77) |
P-value | 0.019 | 0.092 |
IMDC: International Metastatic Renal Cell Carcinoma Database Consortium