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Overall survival according to CTC enumeration or doublets and clusters at baseline. 2A. Arm A: OS for patients with 0 vs 1–4 CTC/7.5 ml WB using revised algorithm. 2B. Arm B/C: OS according to presence or absence of clusters. 2C. Arm B: OS according to presence or absence of clusters. 2D. Arm C: OS according to presence or absence of clusters (See text for definition of Arm A, B, and C).
