. Author manuscript; available in PMC: 2020 Apr 15.

Published in final edited form as: Clin Cancer Res. 2019 Jul 29;25(20):6089–6097. doi: 10.1158/1078-0432.CCR-19-0208

Table 2.

Correlation between CTC cluster(s) and/or doublet(s) in patients with 5–19 vs. ≥20 CTC/7.5 ml WB using the revised algorithm.

	Baseline	Single CTC (no Doublets or Clusters)	CTC with Doublets or Clusters present Any Doublet(s) or Cluster (s)
	Baseline	≥5 CTC	Doublet(s) only	Cluster(s) only	Doublet(s) and Cluster(s)	Any Doublet(s) or Cluster (s)
5–19 CTC	N=103	93 (90%)	5 (5%)	2 (2%)	3 (3%)	10 (10%)
≥20 CTC	N=165	74 (45%)	50 (30%)	9 (6%)	32 (19%)	91 (55%)

p-value of presence of doublets or clusters comparing 5–19 vs. ≥20 CTC/7.5 ml WB: < 0.0001