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. 2019 Jun 26;104(11):1042–1048. doi: 10.1136/archdischild-2018-314822

Table 3.

Injury by cardiac physiology group. Numbers in brackets refer to 95% CI. Altered streaming includes infants with TGA and truncus arteriosus. Left-sided lesions includes CoA and HLHS. Right-sided lesions includes TOF, pulmonary atresia, pulmonary stenosis and tricuspid atresia. P value reflects distribution across cardiac physiology groups compared using χ2 tests

Brain injury type Cardiac physiology group
Altered streaming Left-sided lesion Right-sided lesion Total P value
n % n % n % n %
WMI: all 11 32 (19 to 49) 5 36 (16 to 61) 7 32% (16 to 53) 23 33 (23 to 44) 0.967
WMI category 0.734
 Mild 5 15 (6 to 30) 3 21 (8 to 48) 6 27 (13 to 48) 14 20 (12 to31)
 Moderate 3 9 (3 to 23) 2 14 (4 to 40) 1 5 (1 to 22) 6 9 (4 to 17)
 Severe 1 3 (1 to 15) 0 0 (0 to 22) 0 0 (0 to 15) 1 1 (0.3 to 8)
 WMI with infarct 2 6 (2 to 19) 0 0 (0 to 22) 0 0 (0 to 15) 2 3 (1 to 10)
Arterial ischaemic stroke 3 9 (3 to 23) 0 0 (0 to 22) 0 0 (0 to 15) 3 4 (1 to 12) 0.190
Cerebellar haemorrhage 2 6 (2 to 19) 2 14 (4 to 40) 2 9 (3 to 28) 6 9 (4 to 17) 0.636
Parenchymal haemorrhage 0 0 (0 to 10) 0 0 (0 to 22) 0 0 (0 to 15) 0 0 (0 to 5) 1.000
Venous sinus thrombosis 0 0 (0 to 10) 0 0 (0 to 22) 0 0 (0 to 15) 0 0 (0 to 5) 1.000
Subdural haemorrhage 12 35 (21 to 52) 6 43 (21 to 67) 5 23 (10 to 43) 23 33 (23 to 44) 0.417
Total 34 14 22 70

CoA,  coarctation of the aorta; HLHS, hypoplastic left heart syndrome; TOF, tetralogy of Fallot; WMI, white matter injury.