Table 2.
UPDRS III–IV scores pre‐ and post‐DBS. Lead location and factors precluding further DBS surgeries.
| Patient | UPDRS‐III scores pre‐DBS OFF‐medications | UPDRS‐III scores post‐DBS, ON‐Stimulation and OFF‐ medications | OFF‐time (scale) prior to DBS | OFF‐time (scale) after DBS | Dyskinesias duration(scale) prior to DBS | Dyskinesias duration(scale) after DBS | Lead location, comments, and factors precluding further DBS surgeries |
|---|---|---|---|---|---|---|---|
| 1 | 25 | 18 | N/A | N/A | N/A | N/A | Bilateral STN. Suboptimally placed leads. Cognitive decline contraindicated further DBS surgeries |
| 2 | 28 | 19 | 2 | 1 | 2 | 0 | Right GPI. Well placed lead. Cognitive decline contraindicated further DBS surgeries |
| 3 | 31/34(Left DBS/Right DBS) | 28/23(Left DBS/Right DBS) | N/A left 1(Right) | N/A left 1(Right) | N/A left 1(Right) | N/A left 1(Right) | Bilateral GPI. Well placed leads. Gastroparesis and unpredictable response to oral medications necessitated LCIG therapy |
| 4 | 33 | 26 | 3 | 2 | 3 | 1 | Bilateral STN. Suboptimally placed leads. Elected to pursue LCIG therapy rather than revision DBS surgery |
| 5 | 29 | 22 | 1 | 1 | 4 | 2 | Bilateral STN. Suboptimally placed DBS leads. Severe fluctuations and unpredictable response to oral levodopa necessitated LCIG therapy |
| 6 | 36 | 23 | 2 | 1 | 1 | 0 | Left GPI. Well placed lead. Developed SDH after the first DBS surgery and elected not to have further DBS surgeries |
The off‐time/dyskinesia duration scale 1: 25% or less, 2: 25–50%, 3: 51–75%, 4: 76–100% of waking hours. N/A missing data. Patient 3 had two DBS surgeries 4 years apart.